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KMID : 1034720170090010007
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Journal of Neurosonology and Neuroimaging
2017 Volume.9 No. 1 p.7 ~ p.11
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Subcortical New Diffusion Restricted Lesions are Associated with Acute Manifestation of Vascular Cognitive Impairment
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Kim Do-Yeon
Lee Seon-Kyung
Kim Ah-Won
Kwon Hyung-Min
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Abstract
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Background: Vascular dementia is progressed as a “stair-step” course and this feature becomes important point of difference compared to Alzheimer’s dementia. Aggravation of vascular dementia caused by symptomatic stroke could be diagnosed easily with diffusion-weighted imaging (DWI) sequence of magnetic resonance imaging (MRI) scan, however, cognitive decline in dementic patients is not clearly associated with the extent of white matter hyperintensity (WMH).
Methods: We collected patients who presented acute cognitive impairment with objective diffusion-restricted lesions in DWI sequences from November 2016. Korean mini-mental status examination (K-MMSE) were done in all patients.
Results: There are three depicted cases which showed the onset of vascular cognitive impairment as a progression of WMH, but not explained as a symptomatic ischemic stroke.
Conclusions: Onset of non-stroke, subcortical and periventricular vascular cognitive impairment was observed with DWI and T2 FLAIR MRI scan. If patients are presented with initial and acute-onset cognitive impairment, new subcortical and periventricular white matter disease could be one of differential diagnosis, as well as cortical infarction or strategic infarction.
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KEYWORD
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Vascular dementia, Cognition, Diffusion magnetic resonance imaging, White matter
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